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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d74302f948b9fd3b9db7fd24836885b6789a2e7f3cf6029c29c04571165ff7f' 
  AND token = 'K0ovbZ+CjXnGEDBEEfM3NtE6fIxcgRsjAhHTyrrwdas=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}