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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c34c66f65c6e3830728c954da6dbfeeec35bef96b4337b529dc6e9c2d8527d2' 
  AND token = 'TL1ErmDGkMY3nh9KoifuBfLt2NLSBvnqzVqe1C5xwzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}