SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95c80562ac065c1e720191908af553bb1f8b07c81f6362195bcb9f12e927da14' 
  AND token = '1Y0JMfTyLgmjA3KkPfb4WJ1+rvM4QZOMNFrl93gTj+o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}