SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58960adb04638325f120c85db47e33f9725dca4639388b9edcc9e729a540e65f' 
  AND token = 'sGApqc+a7KjMgvIUyHomqwDuMzSGbecp4TqeXMlSJJo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}