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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b52494193fb875a3d344f85ef79bd0a0db01ec0f33ff31d1eb10a043b8c44e26' 
  AND token = 'EAcReMt3nvdSa4JlN421/BafTyuZ3tLlyV930V7dWuM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}