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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b026d798883bebd261494ad1786579e4015e72b21cc09ab1c6aa8e2904affc4' 
  AND token = 'cW32pPSAxTXOHYB+iRSpzJNaYvj1MvnnBa8nLJRgV14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}