SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8e108d1eb365210c3ed28a95d107c88121941f4f47f9ed1567344432aab9682' 
  AND token = 'ZJQjiS/FyYQNs4GYnfftsdsgs9uONFGSZibxGhdO3fU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}