SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74f7bc75fcc649e824d3ff6842a3e0ab1408ca9cd5952881296355e9d3995946' 
  AND token = 'jbM4G2WeSTEAF356gChwpp6s9CWfh0elgeV5wd2JzvA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}