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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0aff8115c9b18b4802d98bec273c2c2df3e3be6f160db8eed1ee24293ea2ba84' 
  AND token = '7Mcwm0hKctEnb02VOXZYxVl8/Ef7ARNLb8QxtojUnhQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}