SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be7e359f5a04fed8ea3ec9185852ede3b98c0aa8ef271364eee5ce9ef4a68353' 
  AND token = '6k1U6QOJsOEppehjzrb2O3v8bEuwp4NN0h/R6mO2NZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}