SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d8a04e424f56233f15bc6de65820ded1ab82518e40fe8b9d65525ea958f1051' 
  AND token = 'Plm0UyfyI+6Jhho/qo8UxuU54DDoGWSapK1DlAzxCQk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}