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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ffcd6e544b8a6a8243034e480b09cb66d346f1eb6b903dc25032f3be12a681d' 
  AND token = 'fSoYf35ZoMrAhwS0UsUR5zQ/jycbWFV1wUjuKFnNozk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}