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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e5b7cd09e648d5e3db2bf095410830d3f621aca28f8aeeb6294ffa28c1bc15a' 
  AND token = 'ryz87rCDZb1wmF1af2hWSsIk0SC2aCjMrVux694Oy5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}