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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef9e8797a188082db1f4bd5797722a3d91092abdf68b3dd9d78b0da72375d26e' 
  AND token = 'q1UEyyrwzRShbaiRKlf2x1dfarpCLSxz02hPA6VDuiQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}