SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6e6357e5f38fd89f7e7c7b86d11d21e72349996ee9259b28b2c77579e7e7fa5' 
  AND token = 'lxgVxZuKzeQXazr3zoEUcmPVgGrm8I3ymdx3jse6yEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}