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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f181acc654fbe8f1e5efc3639e8537d8e183305b178577ae786d560b6c7e0a7' 
  AND token = '++5uAbpYsmzcletl2AIxENaakcn4HY0NZD2Diml7hEo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}