SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '131b6122cad9ef379a0a252ad62fc5cf38e009646ce3eea0e9084ecf14c87e37' 
  AND token = 'PPEU2A0QO9R5gOndDVV6lLwxq45tqpWDTj5W024Xgzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}