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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '47c0a87934d6a3c004b9bf024db14f1b96d418483741cc2d102f1f5b64f15647' 
  AND token = 'ZJaWucIqwCuOOfdBnvzlnN0XAA43jx7C6W6YfzoySPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}