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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a680cb8f292aa76e3a45ebffb518f1c5373ad4c5ab09dc88a3e25832c86d36a' 
  AND token = 'gq0blVY8HT2RkhlOOsi0cnHwjPhohEiNQUM+XtPa1xw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}