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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb812e7f1e8a02a99f667eb8343e292a91bd12a72cde1e3227703e4ac0b2236c' 
  AND token = 'FH/GOl+FdRP6+sz4K8Kg5Za4bEkGQKIvZdF3dUl57mM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}