SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1059c37914f5cabfc54fdbe63ebe64e24217136abc5dd65e9c19a50c2d29867' 
  AND token = 'Qk1hhSVxV9s7OtCC0Is/D5urFK6dey8EQrKVquXEMFU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}