SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3149946772f9bf4cf4e009414605a904f8b2bbbccd1cbfc09a49a8d393b789e0' 
  AND token = '2YTnAJJF5Bh7u0p1IZA9QrMoN0vMizZwRhscZPThYoE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}