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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ea2d9f6de7e50aa15e8a7230566d6a4da2f80e4c267a30cfa708ac7c40f0289' 
  AND token = 'MwU6x9EDqpurtTQJPZcVoakOyrEDasNIEh45AKMYsGU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}