SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e4670819da39e3b8caa15864e954a5411888e17c8ce433ae71386d74b3eff2c' 
  AND token = 'fv7CfZVNdE4qCDSYY8iNjv0XQZ9P1V50pLjjOt8fUFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}