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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73f2d44e20c2e32e7ea4a2edd6848579e565379ac33e8b347713818eeccf9d28' 
  AND token = '6IG3AY0f4r2sHuJq52c6gJGmJoLDyhiXQ3refyV37o0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}