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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c685d9f0a8c8afe690791f176e7b2b27e32c55852fe80eb8f973ade3beea615' 
  AND token = 'a2gYvbdcxdP3dP+GBNZtrPuYidIjok/hDSlaLmX7ky4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}