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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77c35914b1610e04c1e49a03eb7ce38376f4f4d2611eb38a22d4a65d9185242d' 
  AND token = 'ehfSSpHvFLiZdEzxp3v16rUw+WC5csqL0MU52MJpRj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}