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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b346f7ecf44386cf9f813e863269d9cd833c14246a08b8233bf500c37971e43' 
  AND token = 'mM8laY1010xCCuUc+6ZfA+BbBDs+yqL2IBR5Q95MfwQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}