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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '045a7940014d625515dd43531fb15110a57cf1bcba4e79021be541089291cd25' 
  AND token = 'jfigBEkQYFioUwAs/vqxUEyDTilTri7QyZC/NFdmzyI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}