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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88cc2fcf45a06a65dcf9116a7779ab4cbfda98d6a1e933d6848850f20de7973f' 
  AND token = 'y+ZMVdd2M2g923vN4DMOSkhg+1q7UmD0xs5NcIsngQY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}