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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05f5b977fc59ec103bf8ca4e1586011cfb7dbad81fed4020d7b17e00f7a6b00d' 
  AND token = 'tQEihKtLr62PWJi3cXRAM5jaHrD8R9ToWDtBtzWN9fo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}