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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b65d1cd99febbfe6fd91c2a940ef00115fb9be3cb89214e54d511d8f728bb773' 
  AND token = 'XGNk5XU45xwryIPtFazOGEe8tkOaF5wOhgO08LujPjM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}