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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5ca73c04a16b34aa04b73889bf7863e31847359532e19cb2ba6373ce3486f0e' 
  AND token = 'SZxNE2nSy/fWB8kJTbrAwVDr0koajvpJg7tOpoZ4o/s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}