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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef851677caa6a50721e9bc2ee579e1b75a342c09613d8f2306908e2bc1c903bf' 
  AND token = 'sv6C8q4XFFJ9cbXt+tz1nUooknyQT5CWNHCD9TupRnQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}