SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ec559edd754e75de91496d3db7f50159370aa8cd7dfbf2014cf7ad6f70fe08a' 
  AND token = 'hUX0lILrOnvPoknMGlQeLFd5c470vnhtu9GZZ5ouNwg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}