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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6871e40f774095c1b74973ab1096b8f3ba3264e20a102b413520eb9a82cfdf04' 
  AND token = '8NoWI6i0GABZ2cXiDO1jEtTCURAIng44NCN6mr+EMPI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}