SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2001297b14a6f862badc5bbe87ceff85dc40a68f14393a00b7a4b3a5bb334b7c' 
  AND token = 'qW3xjdRtA8bRLsSShUw4JVlUADpHZaRPOitikprSiLQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}