SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fef6d172d3064a3369a65aa1788210b8950ceb292cbf194154b9ef7aeeca565' 
  AND token = '3nCuWlkUqIlN50ipYasiKxFjQYDFC9h3qt3l/puAlBk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}