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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d7a3e8b1c500b708f4c541d2c170d60b04d441827594589830f077e19003fb8' 
  AND token = 'HwoRPyc09AgO/z3nfUt8IIeEL6QckRBcWRK1IiWdt8I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}