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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '381404602912c98daed08941d2b6b28fb37c4a7688b6d3a9ca70c627afc4a21e' 
  AND token = 'Nmn/yv/r7EFuH5NEmz3NzJNJ8n04hdgES7vng8b7fpM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}