SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd992a520e08b44aec61602e2c4c9a4406d7132c20a474b8aeefc774532b4b725' 
  AND token = 'IvAPcaUfPDLVzLzHz45AYOKMV2nNe4W/tQB1D7S2xKs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}