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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35109cc56c5088f7f43b9874b38327e874a5f122a7a07bd17da4486f08821ac5' 
  AND token = 'oLdHFIaBFpFnf2p6jD2b4PeesKxjWVmcwaQff9+v8Eo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}