SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59116163f88d67d109a6bb0022555a60f75bbd2e60517f674beb949757d5f0f1' 
  AND token = 'VBF1LpNDLInjZ5tXqFoAGdQcQ/gIlrrq14lNhmYB9l8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}