SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ded04c98145af68d638b21b542902cef0d9cb7993fe6779d4d549ed1419d6cad' 
  AND token = 'eQJSxCYusRthKUMkUitL52fHv//OP5aweQo53m6YVag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}