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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f51ed07e949eb49c910d15cabe57c523879cc2c3b9af617e5a85d1f74e9a9d9' 
  AND token = '5wDoOa3n6otnuPfZ+fycWsIQ1wEWSqQP0ran97Q2F2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}