SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00cef3de58eebf784207cb3e178956242b4b2a0e08dfe9eabef457c0b4b327d3' 
  AND token = 'i4Y11UixhXUQKIEGPht9HE5mLoPl6cv4kwO6PtU/pnE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}