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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '604a10a3cbdb9a004d90ff1b3def446c0ac687cf9b91947a4878a3640f131b43' 
  AND token = '4m8BUIyy9pc7vwpzjTzPM0uBSnIJWOs4ywmRYxT9rJI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}