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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '051d67db4171489e8a916561fa773cd96dd6b7fa5da217adc161c77f9b576f44' 
  AND token = 'sLFBq4k0SMyHndqAmtBeoJPy76uEzTHtQCbVNOWQmKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}