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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a8986cffa8d11cc6ae5945cf8c2f883d05f59b140b85064a3c485b364b2d4c9' 
  AND token = 'hjqvuSi+0axGbmnLFA/TWfk2Mf+W+PU6N/ZLCoTHW9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}