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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e7c32296243a3add346d2da9b13372f215de0bd1ec864f1a3f7b17e629cd80b' 
  AND token = '+4RA/Rt8FPWeWlIcl1H8V4n5/5jMuQC3/rRSeKFUMbw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}